@raphoenix I disagree with the disagreement. Most tweaks I have seen are rather detrimental. Think e.g. of "disable indexing". Sure, it saves some CPU cycles, but at the cost of losing powerful near-instantaneous search facilities.
Same goes for RAM cleaners. Sure, you will have more free RAM. Except that free RAM is useless, as RAM-caching results in faster startup of programs and doesn't actually block RAM - cache-contents will just be discarded, when the RAM is needed for immediate tasks.
Even the common "clean reinstall" only results in positive results, if your decvice doesn't strongly depend on proprietary software (such as Fan control, silent mode...) that don't just work after installing drivers and software in the documented order for some reason.
Just that there are things you can "optimize" doesn't mean that it will give you a better experience down the road.
Sadly though, hardware manufacturers might go ahead and apply some common misoptimizations out of the box.